Found 20 matching trials
Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers PHASE1 This study will be a two-part with an open-label, single oral dose, two-way...
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Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF) PHASE2 Daprodustat has demonstrated an ability to effectively raise hemoglobin con...
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Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID) PHASE3 The purpose of this multi-center study is to evaluate the efficacy and safe...
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Anemia Studies in CKD: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat- Iron (ASCEND: Fe) PHASE2 Daprodustat administration has the potential, by virtue of increasing hypox...
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Absorption and Elimination of Radiolabeled Daprodustat PHASE1 Absorption, metabolism and excretion of daprodustat (GSK1278863) have been ...
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Evaluation of Dose Response Relationship, Safety and Efficacy of GSK1278863 in Hemodialysis-dependent Subjects With Chronic Kidney Disease Associated Anemia PHASE2 This study is intended to evaluate the dose-response relationship of GSK127...
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Phase III Study of GSK1278863 in Japanese Non-dialysis (ND) and Peritoneal Dialysis (PD) Subjects With Renal Anemia PHASE3 This is a Phase III, open-label, active-controlled, parallel-group, multi-c...
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Study to Evaluate the Safety and Efficacy of GSK1278863 in Recombinant Human Erythropoietin (rhEPO) Hyporesponsive Hemodialysis-dependent Chronic Kidney Disease Subjects With Anemia PHASE2 The study will evaluate the ability of GSK1278863 to increase the hemoglobi...
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4 Week Switch Study in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease PHASE2 This is a four-week, Phase IIa, randomized, active-controlled, parallel-gro...
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Daprodustat Bioequivalence and Food Effect Study PHASE1 This is two-way crossover study to compare pharmacokinetic (PK) of daprodus...
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